PubChem API

Get PubChem data as clean JSON with one key: 4 endpoints, 1 to 5 credits per call, the same response shape as every other platform.

What you get#

Onekey exposes PubChem as 4 endpoints behind one API key: 3 endpoints return one record (data is an object) and 1 endpoint return a list (data is an array). Every answer uses the same envelope (success, data, metadata, error), the cost is reported in metadata.credits_charged, and fields are mapped onto the unified schema so the code you write for PubChem also works for the rest of the science & research category.

Endpoints#

EndpointWhat it doesParametersCreditsStatus
compound_by_cidChemical compound properties by PubChem CID.cid*1stable
compound_by_nameChemical compound properties by name (PubChem).name*1stable
descriptionTextual description of a compound (PubChem).name*1stable
synonymsSynonyms of a chemical compound (PubChem).name*5stable

A * marks a required parameter. Each endpoint name links to its reference page with the full parameter table, caching window and a recorded response.

Make a request#

This calls pubchem.compound_by_cid (1 credit, stable). Replace YOUR_API_KEY with your key; sign up, no card. 1,000 free credits cover the open-platform endpoints. Hard-to-reach platforms (X, TikTok, Instagram, Reddit, and others marked on their page) need a verified email and a purchased pack.

curl "https://api.onekey.dev/v1/pubchem/compound_by_cid?cid=2244" \
  -H "x-api-key: YOUR_API_KEY"

Fields you get back#

These unified fields come back from PubChem, with the same names as on every other platform. The count is how many of its 4 mapped endpoints return the field; a field the source lacks is null, never missing. 5 platform-specific fields (ext.<name>) come on top, documented on each endpoint page.

FieldTypeEndpoints
entity.idstring3
entity.namestring3
entity.descriptionstring1

The full schema is in Unified schema.

Pricing#

PubChem calls cost 1 to 5 credits, flat per endpoint. Free when served from cache (0.2 credit for a cached response over 100 KB). Invalid, failed or not-found calls are not charged. See pricing for credit packs.